The Pleiades Promoter Project

All MiniPromoters

Ple98-EGFP (Negative)

Other constructs for this MiniPromoter: NONE

Other constructs for this Gene: Ple97-EGFP (Negative), Ple97-lacZ (Positive)

The images are coming soon!

The description is coming soon!

Note: Promoterless negative controls (pEMS1302, pEMS1306, pEMS1313) have been generated, as well as CAG positive controls (pEMS1157, pEMS1277 & pEMS1488).

Ple98-EGFP
	plasmid pEMS1216 (in backbone pEMS1307)
	ESCs mEMS3318, mEMS3319, mEMS3337, mEMS3341
	mice generated using ESC mEMS3318
Resource Files
	Ple98 pEMS1216 Vector NTI File (Requires VectorNTI Sofware)	Holt lab
	Ple98 pEMS1216 Vector Map	Holt lab
	Ple98 pEMS1216 Genotyping Assay (Requires VectorNTI Sofware)	Holt lab

Reference	PubMed ID
Bierl C, Voetsch B, Jin RC, Handy DE, Loscalzo J. Determinants of human plasma glutathione peroxidase (GPx-3) expression. J Biol Chem. 2004 Jun 25;279(26):26839-45. Epub 2004 Apr 19.	15096516
Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children. Comment in: Stroke. 2007 Jan;38(1):6. Stroke. 2007 Jun;38(6):e23; author reply e24. Stroke. 2007 Jan;38(1):41-9. Epub 2006 Nov 22.	17122425
Comhair SA, Bhathena PR, Farver C, Thunnissen FB, Erzurum SC. Extracellular glutathione peroxidase induction in asthmatic lungs: evidence for redox regulation of expression in human airway epithelial cells. FASEB J. 2001 Jan;15(1):70-78.	11149894
Voetsch B, Jin RC, Bierl C, Deus-Silva L, Camargo EC, Annichino-Bizacchi JM, Handy DE, Loscalzo J. Role of promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene as a risk factor for cerebral venous thrombosis. Stroke. 2008 Feb;39(2):303-7. Epub 2007 Dec 20.	18096833
Jee CD, Kim MA, Jung EJ, Kim J, Kim WH. Identification of genes epigenetically silenced by CpG methylation in human gastric carcinoma. Eur J Cancer. 2009 Feb 3; [Epub ahead of print]	19195878